Please click each presentation title to see the abstract.

Opening Remarks & Lectures

Chair: Nagahiro Minato, Kyoto University

9:00-9:05

Opening remarks
Tasuku Honjo (CCII, Kyoto University)

9:05-9:50
Plenary

Neoadjuvant immune checkpoint blockade: a window of opportunity to advance cancer immunotherapy
Suzanne Louise Topalian (Johns Hopkins University School of Medicine)

9:50-10:05

On the biochemical dialog between immune cells mediating anti-cancer responses
Sidonia Fagarasan (CCII, Kyoto University)

Session 1: T Cell Therapy

Chair: Hiroyoshi Nishikawa, CCII, Kyoto University

10:05-10:45

CAR T cells for cancer and beyond
Carl June (University of Pennsylvania)

10:45-11:25

T cells naturally designed and selected to sense and eliminate cancer cells
Hilde Cheroutre (La Jolla Institute for Immunology)

11:25-11:40

Break

Session 2: Myeloid Cells, PD-1 and Beyond

Chair: Osamu Takeuchi, Kyoto University

11:40-12:20

Induction and therapeutic exploitation of PD-1 tolerogenic function
Vassiliki Boussiotis (Harvard Medical School)

12:20-13:00

Liquid biopsy: from discovery to clinical implementation
Klaus Pantel (University Medical Center Hamburg-Eppendorf)

13:00-14:00

Break

Session 3: Immunometabolism

Chair: Sidonia Fagarasan, CCII, Kyoto University

14:00-14:40

High dimensional dissection and therapeutic engineering of the tumor immune microenvironment
Drew M. Pardoll (Johns Hopkins University School of Medicine)

14:40-15:00
Short talk

Novel immune evasion mechanisms involving mitochondria in the tumor microenvironment
Yosuke Togashi (Okayama University)

15:00-15:20
Short talk

Volatile oxidized lipids as noninvasive biomarkers for monitoring ferroptosis in cells, animal models, and human breath
Yuki Sugiura (CCII, Kyoto University)

15:20-15:35

Break

Session 4: Cancer Antigens and Tolerance

Chair: Hideki Ueno, Kyoto University

15:35-16:15

Molecular base of tumor neoantigens: intracellular expression of non-self MHC class I- and II-restricted chimeric epitopes reverses resistance to cancer immunotherapy
Kenji Chamoto (CCII, Kyoto University)

16:15-16:55

Single-cell Treg profiling: new cancer therapies and insights into tumor-Treg biology
Eliane Piaggio (Curie Institute)

16:55-17:35

Cancer-mediated immunosuppression in the tumor microenvironment identified by immuno-genomic analyses
Hiroyoshi Nishikawa (CCII, Kyoto University)